Relaxed phylogenetics and dating with confidence drummond

To learn more or modify/prevent the use of cookies, see our Cookie Policy and Privacy Policy.Disease control programs aim to constrain and reduce the spread of infection.We find no significant rate autocorrelation among branches in three large datasets, suggesting that autocorrelated models are not necessarily suitable for these data.In addition, we place these datasets on the continuum of clocklikeness between a strict molecular clock and the alternative unrooted extreme.Where such control measures fail, the resulting outbreaks can prove extremely costly in terms of public health and economic and political consequences.It is therefore vital to understand the events involved in such transboundary outbreaks of infection and particularly how these events relate to the control measures applied at the boundary.RRV incursions were attributable predominantly to systematic virus leakage of local strains across areas along the border where vaccination has been conducted but also to single stochastic events such as long-distance translocations.These results demonstrate the utility of phylogeographic analysis of pathogen genomes for understanding transboundary outbreaks.

In the United States, the geographic range of the raccoon variant of rabies virus (RRV) has expanded in recent decades and is now endemic throughout the eastern seaboard area ().Finally, we present analyses of 102 bacterial, 106 yeast, 61 plant, 99 metazoan, and 500 primate alignments.From these we conclude that our method is phylogenetically more accurate and precise than the traditional unrooted model while adding the ability to infer a timescale to evolution.We use cookies to make interactions with our website easy and meaningful, to better understand the use of our services, and to tailor advertising.For further information, including about cookie settings, please read our Cookie Policy .

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