Cystic fibrosis dating people with cystic fibrosis

This may cause facial pain, fever, nasal drainage, and headaches.Individuals with CF may develop overgrowth of the nasal tissue (nasal polyps) due to inflammation from chronic sinus infections.

In later stages, changes in the architecture of the lung, such as pathology in the major airways (bronchiectasis), further exacerbate difficulties in breathing.Other signs include coughing up blood (hemoptysis), high blood pressure in the lung (pulmonary hypertension), heart failure, difficulties getting enough oxygen to the body (hypoxia), and respiratory failure requiring support with breathing masks, such as bilevel positive airway pressure machines or ventilators.The most common infection involves bacterial strain mutation to form a biofilm-forming and sustaining mucoid strain on the lung epithelium, which can result in downstream mechanisms that progress the infection.The lack of digestive enzymes leads to difficulty absorbing nutrients with their subsequent excretion in the feces, a disorder known as malabsorption.Malabsorption leads to malnutrition and poor growth and development because of calorie loss.

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